Boost your performance with the top energy supplement.
Feeling fatigued in body and mind? The best energy supplement can help boost both physical and mental vitality. Today's supplements for energy can do this in many different ways.
Beyond tried-and-true caffeine stimulation, energy supplements boost energy production at a cellular level, supply fast-acting fuel for energy, fight the fatigue-inducing effects of stress and more.
Here's the challenge: There are so many natural energy supplement products on the market today. Energy drinks, capsules, energy pills, gummies... you name it. And they're not all good.
In this article, we make it easy for you to choose a quality energy booster that really works!
First we'll do a quick summary of how various energy pills work and how they can be used. We'll follow that by revealing some of today's most effective energy supplement ingredients.
Finally, we'll discuss how these ingredients can be combined for maximum effect with ultramodern vitality supplements Mind Lab Pro®, Performance Lab® Energy, Performance Lab® MCT oil, Performance Lab® Caffeine 2, Performance Lab® NutriGenesis® Multi and Pre Lab Pro®.
Let's get to it!
Experience a Research-Backed Energizing Brain Supplement
Mind Lab Pro® is the world's most effective nootropic supplement. It is scientifically shown to enhance brain function.(1,2)
- Focus, clarity, speed of thought
- 100% safe, clean, plant-based
- Natural energy boost in the brain
- 30 day money back guarantee
- 11 brain supplements in 1 formula
How do supplements boost energy?
Before we get into the individual ingredients, let's get into the many different ways that good energy pills can work to restore vitality throughout the entire body.
Some nutrients contained in these formulas help our cells to generate energy. This is often achieved by optimizing, fueling and protecting the mitochondria powerhouses of each cell.
Other nutrients may help energy levels by regulating the brain chemicals that play roles in alertness and motivation, directly or indirectly helping to increase energy.
Since red blood cells transport energizing oxygen throughout the body, other natural energy boosters will work by supporting blood health and boosting circulation.
Still others boost energy by fighting the fatigue-inducing effects of physical and mental stress.
In addition to working in many different ways, the top energy supplements can target specific aspects of your performance.
For example, nootropic energy pills feature bioactivities that benefit the brain, resulting in revitalized cognitive performance.
Sports nutrition energy supplements -- pre-workout formulas for example -- focus more on raising vitality for physical performance.
Skillfully combining energy nutrients (a practice known as "stacking") may help them to restore energy levels even more effectively.
A single well-designed product may combine several energizing ingredients that function effectively as a team. For even more synergy, you can combine several products to raise energy from multiple angles.
Stacking can be complicated, however. All of the products discussed in this article can be combined safely and effectively, so keep that in mind as you read on.
Let's get into the best individual ingredients found in today's top energy formulas.
Increase energy naturally with these supplement ingredients
Citicoline
The best nootropic for brain energy enhancement and cognitive performance.
Citicoline, a potent brain-boosting compound, can also enhance energy levels via two key pathways:
- Brain chemicals. As a precursor to the neurotransmitter acetylcholine, it aids in cognitive function and communication between brain cells. By optimizing neural pathways, citicoline fosters mental clarity and focus, indirectly contributing to increased energy.
- Mitochondria. Citicoline enhances mitochondrial function, the cell's energy powerhouses, thereby promoting peak cellular energy production.
Citicoline's dual action on neural communication and cellular energy metabolism translates to heightened overall energy levels.
Some of citicoline's research-backed performance benefits are attributed to its energy support in the brain, specifically. In a clinical study on Cognizin® citicoline, researchers linked the supplement to a significant 13.6% increase in ATP energy levels in brain.(3)
Incorporating citicoline into a supplement regimen gives you a versatile tool for both brainpower and energy. It's a real powerhouse to look for in energy pills if you are seeking a mind-body boost.
More on Citicoline here.
Rhodiola Rosea Extract
Rhodiola is a powerful, fast-acting herbal adaptogen that boosts energy by directly countering stress-induced fatigue.
Also known as the "Golden Root," Rhodiola rosea has been used for centuries in traditional Russian herbalism practices for many performance benefits, including as a revitalizing natural energy herb.
Rhodiola rosea is an adaptogen that helps the human body to resist stress and its many negative effects -- including mental and physical fatigue.
It has a good deal of research backing it, but two studies related to Rhodiola for energy include:
- Researchers have suggested that small amounts of Rhodiola Rosea appear to increase electrical activity in the brain.(4) This may support its potential brain energy metabolism benefits
- Researchers reported that Rhodiola works fast and provides sustained energy -- specifically, they found its stimulating effects may be noticeable in 30 minutes and may last up to six hours.(5)
With a unique combination of stress-busting and brain-energizing bioactivities, along with extensive research and a legendary reputation, Rhodiola may be one of the most powerful ways to increase your energy levels naturally -- especially if you are a performance-driven individual.
More on Rhodiola Rosea here.
N-Acetyl L-Tyrosine
N-Acetyl L-Tyrosine (NALT) is an easy-to-absorb form of Tyrosine. It fights low energy levels related to stress, fatigue, overworking, sleep deprivation and other lifestyle factors.
L-tyrosine, a crucial amino acid, plays a pivotal role in enhancing energy levels by serving as a precursor to catecholamine neurotransmitters like dopamine, norepinephrine, and epinephrine.
When the brain is stressed or sleep deprived, it burns through L-tyrosine to make these brain chemicals that you need to stay energized.
When L-tyrosine levels drop, so do performance-driven brain chemicals. Cognitive and physical vitality then crashes -- culminating in that unpleasant state known as burnout.
Especially in the context of a stressful and hectic lifestyle, L-tyrosine supplementation helps restore and maintain the brain chemicals you need for energized peak performance.(6)
NALT's impact on energy levels appears to be validated by studies suggesting it helps to enhance performance under:(7)
- stressful conditions
- fatigue from insufficient sleep
- multitasking scenarios
- distracting conditions (noisy, cold, etc.)
Through its multifaceted impact on neurotransmitter and hormone production, L-tyrosine may effectively raise energy levels and help those seeking improved vitality and mental clarity.
More on N-Acetyl L-Tyrosine here.
Maritime Pine Bark Extract
Pine bark extract, sourced from the maritime pine tree, holds the potential to invigorate energy levels.
Rich in antioxidants called proanthocyanidins, it bolsters blood circulation by strengthening blood vessel walls and enhancing nitric oxide production. Nitric oxide in turn relaxes blood vessels so they open wider, which unleashes a whole-body circulation boost.
With enhanced circulation, energizing oxygen is delivered efficiently to cells, and energy-boosting nutrients are distributed throughout the body.
This is one reason why athletes love nitric oxide supplements: they deliver a natural boost that improves energy in the gym by boosting blood flow to hard working muscles.
- Researchers validate athletes' energizing nitric oxide experience, suggesting that the molecule can indeed enhance performance during exercise.(8)
Pine bark extract's high antioxidant activity also fights oxidative stress in cells, which may further help with fatigue while supporting overall well-being.
More on Maritime Pine Bark Extract here.
MCT Oil
Versatile, fast-acting "alternative fuel" for cells' energy-generating mitochondria.
Medium-chain triglycerides (MCTs), found in certain fats like coconut oil, offer a swift and efficient energy source that can feel like a clean burst of vitality.
Unlike long-chain fats, MCTs are rapidly absorbed and metabolized, bypassing typical digestive processes and going directly to the liver for conversion into ketones.
These ketones serve as readily available fuel for the body and brain, powering heightened alertness and sustained vitality.(9)
MCTs raise ketones that are "burned" by cells to crank up energy production.
MCTs also support thermogenesis—the calorie-burning process—and can help control appetite, indirectly contributing to sustained energy levels.
By providing a quick energy boost and metabolic support, MCTs are a valuable addition to diets for those seeking enhanced endurance and cognitive sharpness.
Unlike the other energy supplements on this list, MCT oil can be incorporated into foods as part of a healthy diet. MCTs can be added to salad dressings, smoothies, etc. to impart them with extra fuel for cell energy generation.
(SEE: Performance Lab® MCT)
Enhanced Caffeine
Next-gen stim combines caffeine with restorative and balancing nutrients for a cleaner power surge.
It's technically a stimulant, but it is hard to deny: Caffeine is the most widely used energy boosting supplement in the world.
Found in products like coffee, green tea extract and energy drinks, caffeine works by blocking receptors of adenosine, a neurotransmitter that tells the brain to feel fatigued and sleepy.
By blocking fatigue, caffeine sustains energy.
But here's the problem: Most supplements and energy drinks fail at raising energy levels in a way that is clean and productive. Instead, they opt for super-stimulating megadoses that come with so many side effects, it's impossible to think straight!
The trick in maximizing caffeine's potential is to go with a low-to-moderate dosage and stack it with L-Theanine and B vitamins, both of which can help to optimize caffeine benefits while minimizing its jitters and other side effects.
(SEE: Performance Lab® Caffeine 2)
Coenzyme Q-10 (CoQ10)
Energizing antioxidant that plays key roles in powering all life on earth.
Coenzyme Q10 (CoQ10), a vital compound in cellular energy production, plays a pivotal role in boosting energy levels. It is a key player in bioenergetics: the flow of energy that enables all life to exist.(10)
Found in every cell's mitochondria, CoQ10 facilitates production of adenosine triphosphate (ATP), the primary energy currency of cells.
Without CoQ10, cells cannot produce energy. While CoQ10 enhances cell energy generation throughout the body, it is most highly concentrated in organs that use a lot of energy, especially the brain and heart.
Additionally, its antioxidant properties protect cells from damage, optimizing overall energy efficiency. Incorporating CoQ10 supplements can effectively support sustained energy, vitality, and overall well-being.
(Find CoQ10 in: Performance Lab® Energy)
PQQ
The best mitochondria booster known to science, PQQ helps energize vitality on a cellular level.
Pyrroloquinoline quinone (PQQ), a micronutrient with potent antioxidant properties, can significantly boost energy levels.
PQQ plays a crucial role in cellular mitochondria, promoting mitochondrial biogenesis—the creation of new powerhouses in each cell. Some researchers have even suggested that PQQ may help to multiply mitochondria.(11)
By stimulating mitochondrial growth and function, PQQ optimizes energy generation, benefiting various tissues like the brain and muscles.
PQQ's formidable antioxidant activity, suggested to be thousands of times greater than that of vitamin C, also protects mitochondria from free radical damage -- helping to support their energy boosting properties across virtually all the body's cells.
Its unique ability to enhance mitochondrial function and combat oxidative damage makes PQQ a promising supplement for elevating energy levels and overall vitality.
(Find PQQ in: Performance Lab® Energy)
Vitamins and Minerals
Low intake of essential nutrients can cause fatigue that is easily reversed with smart supplementation.
In addition to the dynamic energy supplements listed above, basic essential vitamins and minerals also support vitality. The top minerals and best vitamins for tiredness and lack of energy include:
Iron: Iron shortfalls are worse for women, who lose the key mineral via blood loss during heavy periods. Iron deficiency anemia that follows can manifest as fatigue.(12)
Iron supplements can help, especially a quality multivitamin that is customized for women's distinct nutritional needs. Sufficient iron helps red blood cells to transport oxygen that is required for energy.
B Vitamins: In addition to helping keep nerve cells healthy, the B complex includes vitamins that are required for cell energy and overall vitality.
Supplements with vitamin B12 may be most famous for liberating energy from foods we eat, and may assist with chronic fatigue.
Magnesium: This mineral is involved in over 700 life-sustaining bioactivities, including helping the body produce energy. In fact, if magnesium is not present, then cell energy cannot be generated.(13)
A magnesium supplement can help restore optimal levels for energy generation.
(SEE: Performance Lab® NutriGenesis Multi)
What about Chronic Fatigue?
We can't write an article about energy booster products without mentioning chronic fatigue syndrome, a widespread challenge in today's hectic world. Key supplements to consider for chronic fatigue include:
- Coenzyme Q10 and PQQ. Suggested to potentially help with chronic fatigue.
- Adaptogenic herbs like Rhodiola rosea and Ashwagandha aid stress adaptation
- Vitamin D and B-complex vitamins to fight chronic fatigue and optimize energy metabolism.(14)
- Omega-3 fatty acids to regulate inflammation and enhance cognitive function.(15)
In addition to energy supplements, lifestyle practices like a balanced diet, regular exercise, quality sleep, and stress reduction techniques like meditation or yoga can also help with chronic fatigue.
Best Energy Supplements of 2025
Now that we've covered many of the top energy boosting ingredients, let's take a look at the supplements that deliver them to you.
Best Nootropic for Mental Energy: Mind Lab Pro
Since cognitive performance depends on brain energy production, Mind Lab Pro® supplies some of the top stim-free nootropics for unleashing a focused energy boost.
But that's just the beginning of what the world's greatest nootropic supplement can do.
Mind Lab Pro® functions as a whole-brain optimizer - unlocking significant improvements across focus, learning, memory, motivation, relaxation, stress resistance and more while nourishing the brain for long-range health and clarity. Its nootropic ingredients include several of the energizers discussed in this article and more:
- Citicoline, 250 mg
- Phosphatidylserine, 100 mg
- Bacopa Monnieri, 150 mg (24% bacosides, 9 bioactives)
- Organic Lion's Mane Mushroom, 500 mg (full spectrum extract)
- Rhodiola Rosea, 50 mg (3% rosavins, 1% salidrosides)
- L-Theanine, 100 mg
- L-Tyrosine, 175 mg (N-Acetyl L-Tyrosine)
- Maritime Pine Bark Extract, 75 mg (95% proanthocyanidins)
- Vitamin B6 2.5 mg, vitamin B9 100 mcg, vitamin B12 7.5 mcg (NutriGenesis®)
Mind Lab Pro® is Backed by Research.
Mind Lab Pro® is one of the only nootropic supplements on the market that has been the subject of rigorous clinical human trials.
- In one study, researchers reported that subjects taking Mind Lab Pro for 30 days experienced significant improvements (when compared to those taking placebo) in performing information processing tasks involving simple reaction time (SRT), choice reaction time (CRT) and anticipation.(1)
- A second study found that subjects taking Mind Lab Pro demonstrated significant improvements across all memory functions that were tested, including auditory, visual, visual working, immediate and delayed recall memory.(2)
To get the best deal on Mind Lab Pro, click here.
Top Supplement for Overall Energy: Performance Lab® Energy
Performance Lab® Energy is the top natural energy supplement overall. It provides a clean sustained energy boost with zero jitters or crashes.
Energy vegan capsules achieve this with an advanced formula design that includes:
- Magnesium (as Malate), 60 mg
- MicroActive® Q10 (CoQ10), 100 mg
- BioPQQ® (Pyrroloquinoline Quinone), 10 mg
- Acetyl-L-Carnitine (ALCAR), 750 mg
- BioPerine® Black Pepper Extract, 2.5 mg
- Bio-Enhanced® R-Lipoic Acid, 150 mg
Because it features all of the best mitochondrial nutrients, Performance Lab® Energy can boost your body's energy stores like no other product can -- all without relying on stimulation.
This is an energy and metabolism supplement that works naturally and organically within the body. Its natural vitality capsules produce energy boosting benefits you can really feel.
To get the best deal on Performance Lab Energy, click here.
Top Caffeine Energy Supplement: Performance Lab Caffeine 2
Do you prefer your natural energy boosters with a nice caffeinated buzz?
Performance Lab® Caffeine 2 is an enhanced caffeine supplement that includes amino acids and B-vitamins that produce a cleaner, easier state of energized stimulation. It includes:
- Natural Caffeine, 50 mg
- L-Theanine, 100 mg
- L-Tyrosine, 250 mg
- NutriGenesis® Caffeine Balance B-Complex
These natural vitality capsules are presented in 50 mg caffeine increments so you can pinpoint the dosage that works best for you. Take 1-4 capsules total. It is a remarkably simple way to maximize caffeine's benefits.
To get the best deal on Performance Lab Caffeine 2, click here.
Best MCT for Energy: Performance Lab® MCT oil
Performance Lab® MCT oil is a clean, premium-quality source of fuel for cell energy.
It supplies the best C8/C10 MCTs from 100% non-GMO organic coconuts. This helps unlock peak MCT energy benefits, including a natural energy boost, without the indigestion associated with plain coconut oil or low-quality MCT formulas.
Other features of this top energy and metabolism supplement include:
- Neuroprotective, supporting both long-range brain health and mental energy levels
- C8/C10 MCTs: More potent, effective and easier to digest than coconut oil
- State-of-the-art MCT: Clean, pure, triple-filtered and calibrated to 60% C8 and 40% C10
- Flavor-neutral, mixes easily into coffee, shakes, smoothies, dressings
To get the best deal on Performance Lab MCT, click here.
Best Energy Multivitamin: Performance Lab NutriGenesis Multi
Before taking any other energy pills, you should probably start with a high-quality multivitamin.
NutriGenesis® Multi is the cleanest, healthiest, easiest-to-absorb multivitamin. It supplies NutriGenesis® vitamins and minerals in gender-specific formulas calibrated for peak health benefits.
- Supplies 27 vitamins and minerals, including 100%+ Daily Value of the 17 essentials
- NutriGenesis® vitamins and minerals are bound with absorption-enhancing whole-food cofactors
- Completely free of hard-to-absorb synthetic nutrients and isolated nutrient forms
An energy multivitamin, it supplies B-complex (including B12), iron to reverse iron deficiency anemia, along with magnesium and other key vitamins for energized muscle and nerve function.
To get the best deal on Performance Lab® NutriGenesis Multi, click here.
Best Energizing Pre-Workout Supplement: Pre Lab Pro® by Performance Lab®
Introducing Pre Lab Pro, an innovative pre-workout energy formula that embraces a refined approach to supplementation.
Its ingredients include several energy boosters on this list:
- Red Beetroot Powder
- Setria® Performance Blend
- Natural caffeine
- L-Tyrosine
- L-Theanine
Enriched with intelligent caffeine, hydration-supporting nutrients, energy support and vital vitamins/minerals, Pre Lab Pro is your ultimate workout companion for both cardio and strength training.
- Elevate athletic performance, cognitive prowess, and fat-burning capabilities.
- Tailored for strength, power, stamina, endurance, speed, muscle recovery, and growth.
- Experience a unique, precision-engineered caffeine blend for sustained, crash-free energy
- Need a break from energy pills? Pre Lab Pro mixes into a delicious berry flavored energy drink.
- No artificial sweeteners, preservatives, or weird unnecessary fillers
Distinguished by its ability to restore depleted vitamins and brain chemicals resulting from training, Pre Lab Pro stands as a remarkable pre-workout supplement unlike any other.
To get the best deal on Pre Lab Pro®, click here.
All the above products sell on www.performancelab.com where you can find even more energy supplements, as well as many other health and fitness supplement products.
Conclusion
Mind Lab Pro® + Performance Lab® + Pre Lab Pro® supply today's best energy supplements in clean, premium-quality formulations that stack together seamlessly.
For long-term energy enhancement, these natural dietary supplements work and are safe for daily, long-term use. Take these energy supplements, start exercising regularly, get enough sleep and follow a healthy diet. Your energy will go through the roof, naturally.
