Fiber and Fasting Protocol: Does Prebiotic Fiber Break A Fast?

  • By Performance Lab
  • 10 minute read
Fiber and Fasting Protocol: Does Prebiotic Fiber Break A Fast? An illustration of a clock with food.
  • image of Kinga Jasiak, ANutr, BSc Nutrition and Health
  • Expert reviewed by Kinga Jasiak, ANutr, BSc Nutrition and Health

Intermittent fasting is everywhere—with some sources referring to it as the 'secret weapon' to losing belly fat.

Not only is it revered for its weight loss benefits, this eating pattern is also believed to reduce insulin resistance and inflammation. Improve heart and brain health, play a role in disease prevention, and even help you live longer!1

Honestly, what's not to love about it?

Well, one concern for newcomers—aside from battling those initial hunger pangs, is the lack of nutrients that comes from a reduced food intake.

How can we maintain essential nutrients during fasting periods?

This raises an important question: what can you consume that supports your health without breaking your fast?

Prebiotic fiber often enters this conversation, sparking debate over whether it fits within fasting protocols or disrupts them altogether.

Let’s explore the science and see where prebiotic fiber stands—starting with a closer look at intermittent fasting itself, and why everyone is doing it.

Key Takeaways

Not got time? No problem. Here are the highlights:

  • Intermittent Fasting Benefits: Fasting supports weight loss, metabolic health, cellular repair, and brain function by leveraging natural processes like autophagy, ketosis, and improved insulin sensitivity.
  • Supplements and Fasting: Not all supplements are fasting-friendly, but prebiotic supplements can be a great addition to maintain gut health without breaking your fast.
  • Prebiotic Fiber Benefits: Prebiotic fiber promotes weight loss, supports heart health, lowers blood sugar, boosts brain function, improves gut conditions, and reduces inflammation. Making it a no-brainer choice that synchronizes with your original intermittent fasting goals.
  • Why Choose Prebiotic Supplements? Prebiotic supplements like Performance Lab® Prebiotic provide all the benefits of prebiotics without the calories from prebiotic-rich foods that would break a fast.
  • Performance Lab® Prebiotic: With just 4 calories per serving, it supports your gut microbiome during fasting while respecting key fasting principles like autophagy and ketosis.

What is Intermittent Fasting?

What is Intermittent Fasting? A blue plate with a spoon and fork set at either side. On top of the plate is a clock. The hands are set to 5 past 8. on the clock face between the hours of 1 and 6, food is laid out.

Intermittent fasting (IF) involves cycling between periods of eating, and periods of abstaining from food or drinks that contain calories.

There are plenty of fasting plans to follow, so choose whatever works best for your lifestyle and goals.

Here are the most popular:

16/8 Fasting (Time-Restricted Eating)

  • What It Is: You have an 8-hour eating window and 16-hour fasting period.
  • Why It’s Popular: Easy to integrate into daily routines—many people simply skip breakfast.
  • Who It’s For: Beginners and those seeking weight loss or general health improvements.

5:2 Fasting (The Fast Diet)

  • What It Is: Eat normally for five days a week and consume 500–600 calories on the other two days.
  • Why It’s Popular: Offers flexibility without requiring daily fasting.
  • Who It’s For: People looking for a moderate approach to calorie restriction.

Eat-Stop-Eat

  • What It Is: Fast for 24 hours once or twice a week, typically from dinner to dinner.
  • Why It’s Popular: Simple to understand, with no need to calculate eating windows or caloric intake.
  • Who It’s For: Those who can handle extended fasting without frequent hunger issues.

The great thing about intermittent fasting is that you're not restricted on what food you should eat during the eating period. Which is a big reason why intermittent fasting is such an attractive and sustainable diet for many.

How Does it Work?

Intermittent fasting (IF) isn't just about skipping meals—it's rooted in biological processes that help the body adapt, repair, and thrive during periods without food.

At its core, fasting triggers a series of metabolic shifts and cellular responses designed to optimize energy use and support long-term health. Here's a closer look at the science:

Cellular Repair and Autophagy

During fasting, the body initiates autophagy, a process that clears out damaged cellular components and recycles them for energy. This helps reduce oxidative stress and inflammation, supporting long-term health and cellular efficiency.

Ketosis and Fat Burning

Once glycogen stores are depleted, the body shifts to ketosis, where it burns fat for fuel. This produces ketones, which provide energy for the brain and body while preserving muscle mass and enhancing fat metabolism.

Insulin Sensitivity

Fasting lowers insulin levels, improving the body’s response to this critical hormone. Enhanced insulin sensitivity supports blood sugar control and may reduce the risk of type 2 diabetes and other metabolic disorders.

By leveraging these natural processes, intermittent fasting optimizes cellular repair, energy production, and metabolic health.

Health Benefits of Intermittent Fasting

Weight Loss and Fat Burning

Weight Loss and Fat Burning . A white body scale with a green tape measure wrapped around it against a yellow background

Reduced Caloric Intake: If you restrict calories to a limited window, many people naturally consume fewer, without consciously trying to diet.

The shortened 'eating window' reduces opportunities for snacking and overeating, leading to a calorie deficit that supports weight loss.

Lowered Insulin Levels: Fasting lowers insulin levels, encouraging the body to tap into stored fat reserves for energy.

Preservation of Lean Muscle Mass: Unlike some calorie-restriction diets that may lead to muscle loss, intermittent fasting can help preserve lean muscle mass.

Fasting stimulates the production of human growth hormone (HGH), which supports muscle maintenance and growth.2

Improved Metabolic Health

Intermittent fasting supports metabolic health by improving key markers:

  • Lower Insulin Levels: Fasting enhances insulin sensitivity, helping the body manage blood sugar more efficiently and potentially reducing the risk of type 2 diabetes.
  • Stable Blood Sugar: By reducing blood sugar levels and minimizing fluctuations, fasting promotes better energy balance throughout the day.
  • Improved Cholesterol: Studies suggest fasting may lower LDL ("bad") cholesterol and triglycerides, contributing to heart health.3

Cellular Repair and Autophagy

Cellular Repair and Autophagy. Muscle fibres showing cell regeneration.

Intermittent fasting triggers autophagy, the body's natural process of clearing out damaged cells and regenerating new ones. This reduces oxidative stress and free radicals, protecting cells from damage and potentially slowing the effects of aging.

Enhanced Brain Function

Fasting boosts brain-derived neurotrophic factor (BDNF), a protein essential for learning and memory. Additionally, it may offer neuroprotective benefits, with studies suggesting it could reduce the risk of neurodegenerative diseases like Alzheimer's and Parkinson's.

The benefits of intermittent fasting are clear. Maximizing its impact often comes down to the details—like what, if anything, you consume during your fasting window.

Is there anything that's ok to consume?

This is where supplements enter the conversation.

Supplements And Intermittent Fasting

Supplements And Intermittent Fasting. A plue plate on a pink background filled with brightly colored assorted supplements.

One of the big questions when fasting is how to stay healthy and keep your body supported without accidentally breaking your fast.

Supplements can be a helpful way to fill any gaps, especially during longer fasting periods, but not all of them are fasting-friendly.

Some supplements, like those with added sugars or proteins, contain enough calories to cause a metabolic response—potentially disrupting the benefits of fasting like ketosis or insulin sensitivity.

That’s why choosing the right supplements matters.

Prebiotic supplements are a little different. These gut-health heroes are generally calorie-free and work behind the scenes to support your microbiome, even when you’re fasting.

But here’s the catch—not all prebiotic sources are the same. Some prebiotic-rich foods will add calories and break your fast, while supplements can provide the benefits without the extras.

Let’s take a closer look at prebiotic fiber and why it could be the ultimate fasting-friendly companion.

Benefits of Prebiotic Fiber

Your gut is home to trillions of microorganisms that make up your gut microbiome—a delicate balance of “good” and “bad” bacteria.

The beneficial bacteria play vital roles in digestion, nutrient absorption, energy levels, mood, and immunity. On the flip side, harmful bacteria are linked to inflammation, weight gain, and a higher risk of disease.

Maintaining a diverse microbiome with plenty of “good” bacteria is essential for overall health. But when this balance is disrupted—known as dysbiosis—it can negatively impact your well-being.

Learn more about the link between mood and food

The food you eat plays a big role in supporting your gut bacteria, and this is where prebiotic fiber shines. Found in fruits, vegetables, beans, and whole grains, prebiotic fiber isn’t digested by your body. Instead, it travels to the large intestine, where it becomes food for “friendly” bacteria, helping them thrive and promoting a healthier gut.

Prebiotic Fiber Supports Your Fasting Goals

Depending on the health goal that brought you to intermittent fasting, prebiotic fiber can complement many of those objectives, making it an ideal addition to your fasting protocol. Here’s how:

Promotes weight loss: Studies have found that probiotics and prebiotics taken together can support weight and fat loss in overweight or obese individuals.4

Improves heart health: Good gut bacteria, fueled by prebiotics, may help reduce cholesterol levels,5 benefiting heart health and lowering the risk of heart disease, heart attacks, and stroke.

Lowers blood sugar: Prebiotics have been found to help reduce blood sugar and fasting insulin levels, which is especially beneficial for individuals with diabetes or prediabetes.6

Boosts brain health: The gut-brain connection means a healthy microbiome helps produce essential brain chemicals like serotonin, which regulate mood. According to research, a lack of healthy bacteria can contribute to anxiety and depression.7

Improves gut conditions: Prebiotic fiber can improve gut health by feeding probiotics responsible for helping to alleviate irritable bowel syndrome symptoms and constipation.8

Reduces inflammation: Inflammation underpins nearly all chronic diseases. Prebiotic fiber can help reduce inflammation by improving the health of the intestinal lining and inhibiting the action of inflammatory molecules.9

Prebiotic fiber tackles a range of health goals, making it the perfect partner to amplify the benefits of intermittent fasting.

Why Prebiotic Supplements Are Best for Fasting

When following a fasting diet, you will want to avoid these prebiotic-containing foods like fruits and whole grains, as they contain calories and will break your fast.

For this reason, prebiotic dietary supplements are the best choice—they offer all the gut-supporting benefits without interfering with your fasting window.

How Prebiotic Supplements Can Support Intermittent Fasting

Supports Gut Health During Fasting: Even though you’re not eating, your gut bacteria are still active. Prebiotic supplements provide the “fuel” for beneficial bacteria, helping to maintain a healthy and diverse microbiome throughout the fasting period. A well-supported microbiome ensures your digestive system is ready to process food efficiently when the fast ends.

May Reduce Digestive Discomfort After Eating: After fasting, some people experience digestive upset, particularly if they break their fast with heavy or nutrient-dense meals. Prebiotic fiber helps prepare the gut by fostering beneficial bacteria, which aid in breaking down food and reducing bloating or discomfort after eating.

Supports Nutrient Absorption: Prebiotics promote the growth of bacteria that produce short-chain fatty acids (SCFAs), which improve gut lining integrity and nutrient absorption. This means your body can better utilize the vitamins, minerals, and other nutrients in the first meal after fasting.

Helps Maintain Regularity: Fasting can sometimes slow digestion, leading to constipation for some individuals. Prebiotics keep things moving by promoting healthy gut motility.

Best Prebiotic for Intermittent Fasting: Performance Lab® Prebiotic

When it comes to fasting, even the tiniest details matter—including caloric content. While technically any amount of calories could break a fast, it’s important to consider the bigger picture: the impact on your metabolic state and fasting goals.

Performance Lab® Prebiotic contains just 4 calories per serving, an amount so minimal that it’s unlikely to disrupt key fasting benefits like autophagy, ketosis, or insulin sensitivity.

Performance Lab® Prebiotic

This makes it an excellent choice for those who want to maintain gut health during fasting without compromising their progress.

Why Performance Lab® Prebiotic Works for Fasting

  • Minimal Caloric Impact: With only 4 calories, it supports your gut microbiome without causing significant metabolic shifts.
  • Fasting-Compatible Ingredients: Featuring Orafti® Synergy1, a premium prebiotic fiber from chicory root, it fuels beneficial gut bacteria without added sugars or fillers.
  • Supports Gut Health: Helps maintain a balanced microbiome during fasting, keeping your digestive system primed for when you break your fast.

Fasting is about making choices that align with your goals. Performance Lab® Prebiotic offers the perfect balance, supporting your gut while respecting the principles of intermittent fasting.

  1. Wilhelmi de Toledo, Françoise, et al. "Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition." Annals of medicine 52.5 (2020): 147-161.
  2. Hollstein T, Basolo A, Unlu Y, Ando T, Walter M, Krakoff J, Piaggi P. Effects of Short-term Fasting on Ghrelin/GH/IGF-1 Axis in Healthy Humans: The Role of Ghrelin in the Thrifty Phenotype. J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3769-e3780. doi: 10.1210/clinem/dgac353. PMID: 35678263; PMCID: PMC9387714.
  3. Malinowski B, Zalewska K, Węsierska A, Sokołowska MM, Socha M, Liczner G, Pawlak-Osińska K, Wiciński M. Intermittent Fasting in Cardiovascular Disorders-An Overview. Nutrients. 2019 Mar 20;11(3):673. doi: 10.3390/nu11030673. PMID: 30897855; PMCID: PMC6471315.
  4. Álvarez-Arraño, Valentina, and Sandra Martín-Peláez. "Effects of probiotics and synbiotics on weight loss in subjects with overweight or obesity: A systematic review." Nutrients 13.10 (2021): 3627.
  5. Fu, Jingyuan, et al. "The gut microbiome contributes to a substantial proportion of the variation in blood lipids." Circulation research 117.9 (2015): 817-824.
  6. Wang, Long, et al. "Inulin-type fructans supplementation improves glycemic control for the prediabetes and type 2 diabetes populations: results from a GRADE-assessed systematic review and dose–response meta-analysis of 33 randomized controlled trials." Journal of translational medicine 17.1 (2019): 1-19.
  7. Clapp, Megan, et al. "Gut microbiota’s effect on mental health: The gut-brain axis." Clinics and practice 7.4 (2017): 987.
  8. Bărboi, Oana-Bogdana, et al. "Effect of inulin in the treatment of irritable bowel syndrome with constipation." Experimental and Therapeutic Medicine 20.6 (2020): 1-1.
  9. Fortuna, Rafael, et al. "Effect of a prebiotic supplement on knee joint function, gut microbiota, and inflammation in adults with co-morbid obesity and knee osteoarthritis: study protocol for a randomized controlled trial." Trials 22.1 (2021): 1-10.